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It does not cause weight gain and carries a low risk of low blood sugar (hypoglycaemia) when used alone

(PubMed) US Department of Health and Human Services, National Institutes of Health, Office of Dietary Supplements

However, people taking this vitamin must be careful as one of the ingredients in Vitamin B12 may cause some Eye disease and may interact with alcohol

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Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury