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The interplay between T cells and dendritic cells is promoted by pdpn-expressing fibroblastic reticular cells in conjunction with pdpn + stromal fibroblasts, facilitating the transition from innate to adaptive immunity within TLS (38, 142, 143)

Wan et al., Engineering multienzyme-mimicking covalent organic frameworks as pyroptosis inducers for boosting antitumor immunity

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COOL BEFORE OPENING

3.3.1 Antioxidant activity Substances such as shikonin, alkanin, lawsone, emodin, epigallocatechin-3-gallate, and ellagic acid, along with certain herbal extracts, act as potent antioxidants by scavenging reactive oxygen species (ROS), inhibiting lipid peroxidation, and enhancing the activities of intracellular antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)