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The absence of both 5' caps and 3' polyadenylated tails renders circRNAs resistant to exonuclease-mediated degradation, thus ensuring their stability and longevity in cellular processes (158)

A generation mechanism of triboelectricity due to the reaction of mechanoradicals with mechanoions which are produced by mechanical fracture of solid polymer

In addition, natural compounds can increase the level of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that regulates the expression of antioxidant and cytoprotective genes through the antioxidant response element (ARE), where their levels are decreased in PD (Aguiar et al

this was validated in U373 and patient-derived stem-like cells

It has completed a low-irritation skin test and confirmed the skin-delivery characteristics of its active ingredients through a human skin permeation evaluation conducted by the Skin Biotechnology Center, recording cumulative sales of 180,000 sets, or about 3.64 million sheets, in the year since launch