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Blood samples were obtained from the catheter in the jugular vein, and urine samples were obtained from the bladder catheter

In fact, ROS-modulating therapies share certain similarities with existing treatments such as chemotherapy and immunotherapy, that is, pro-oxidative stress strategies to further kill tumor cells and other cells, which has been recognized as a promising approach to improve treatment outcomes for decades [564, 565]

The average survival time after being diagnosed with ALS is three to five years

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