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10.1016/j.clon.2021.06.007 307 ShenK.-Y.DaiX.-L.LiS.HuangF.ChenL.-Q.LuoP.et al (2023)

163 In addition to glycolysis, the tricarboxylic acid (TCA) cycle and oxidative phosphorylation can be activated in the cell-free context

These radicals, oxLDL in particular, are recognised and internalised by circulating monocytes which initiate foam cell development and macrophage infiltration into blood vessels ( Reference Quinn, Parthasarathy and Fong 87 )

Of note, enhancing the spatiotemporal specificity of ATF-targeting interventions is critical for improving therapeutic efficacy and safety

Additionally, the CBS enzyme participates in a desulfation reaction to help create hydrogen sulfide, H2S