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Fibroblast growth factor 1 (FGF1) is the upstream regulator of the PI3K/AKT signaling pathway and is also implicated in neuroprotection and cellular resilience, making this signaling axis a compelling target to be explored in AD 10,11,13

& Biessels, G

Recent studies have emphasized the significance of ferroptosis, an iron-dependent mechanism of programmed cell death, in the degeneration of nucleus pulposus cells (NPCs)

Abstract Copper homeostasis in Gram-positive bacteria essentially requires three components: a copper exporting ATPase (founding member CopA), a copper chaperone (founding member CopZ), and a copper-responsive regulator (founding member CopY) which regulates the expression of these functions