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However, we note that this was based on comparing two separate phase 3 trials, which can involve numerous confounding variables, and the applicant did not provide support related to clinical trial design or statistical analysis to explain why the potential effect of confounding variables should not be a concern for purposes of this comparison

Data availability Raw data described in the manuscript will be made available upon request pending: References Jain, A

In any patient with spontaneous hematoma and purpura, in the context of nutritional disorder, scurvy should be systematically considered