chac1 er stress glutathione degradation CHAC1: a master regulator of oxidative and ferroptosis in human diseases and cancers Human CHAC1 Protein Degrades Glutathione,

Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element* Journal of Biological Chemistry The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2: Cell Reports BACH1CHAC1Glutathione Axis Aggravates Myocardial IschemiaReperfusion Injury by Enhancing Ferroptosis and Oxidative Stress CHAC2 is essential for self renewal and glutathione maintenance in human embryonic stem cells ScienceDirect CHAC1 degradation of glutathione enhances cystine starvation induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2 eIF2 ATF4 pathway Oncotarget

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