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10.1161/CIRCULATIONAHA.110.958033 Circulation 73 HsuehY

Ihle NT, Powis G, Kopetz ES

These conversions result in the production of glucuronide and sulfate, curcumin compounds that render curcumin more bulky (which further limits curcumin uptake across the gut wall, meaning that a significant proportion of curcumin is excreted unabsorbed in the faeces) and water-soluble (allowing any absorbed curcumin to be easily excreted by the kidneys)

The determination of cell proliferation rate was based on the ratio of total and Ki67 + nuclei and the quantification of ICAM and VCAM expression per cell was calculated according to the formula CTCF (corrected total cell fluorescence) = integrated density (area of selected cell mean fluorescence of background reading), both using ImageJ software (imagej.nih.gov/ij/ )