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While there is data to suggest that the drugs doxorubicin and cyclophosphamide, often used in the treatment of childhood leukemia or brain cancers, may cause neuropathy, there is insufficient evidence of this in pediatric populations and therefore will not be included in this review (Lipshultz et al., 1991

So in theory L-carnitine should be extra relevant here, because: More fat has to get into the mitochondria

Gut 66 (7), 12161224

Th17 and cognitive impairment: possible mechanisms of action

Eligible adults include those with an initial BMI of 30 kg/m 2 and above, or 27 to 29.9 kg/m 2 in the presence of at least one weight-associated comorbidity