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DOI: 10.1038/s41467-017-01114-1 Formulation strategies for therapeutic peptide stability pH, ionic strength, co-solvency

A separate human trial found that topical GHK-Cu produced collagen increases in 70% of the women treated outperforming both vitamin C and retinoic acid

treatment and care costs are presently $70-100 billion [12] and worldwide more than $600 billion [13] , a number predicted to reach $3 trillion by 2050 [11]

Computing the effect of pH and ionic strength on viscosity-correlated descriptors could be a useful starting point for formulation composition design, enabling selection of solution conditions from which to begin testing viscosity-reducing excipients