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At week 68, the mean weight reduction in the CagriSema group was 13.7%, compared with 3.4% in the placebo group, yielding a significant between-group difference of 10.4% (95% CI: 11.29.5

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Moreover, resistance to auranofin may occur due to the aberrant expression of multiple drug transporters (e.g., SLC22A1, SLC47A1, SLCO1B1, and ABCBs) in cancer cells [239]

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