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All these results suggest that Cys47 plays a key role in intersubunit cooperativity and that under certain pathological conditions S-nitrosylation of Cys47 by GSNO is a likely physiological scenario

This detoxification process eventually leads to improved skin health and brighten the skin

doi: 10.3390/ijms22115675 26 ZhangLDingFWuXWangRWanYHuJet al

Frenkel D, Huang Z, Maron R, Koldzic DN, Hancock WW, Moskowitz MA, et al

However, as mentioned earlier, fungal GDHs lack the complex antenna-mediated allosteric machinery found in mammalian GDH, as their regulation is primarily transcriptional and allosteric regulation is operative through domain interactions [49]