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320 It is classified as one of the mitochondrial encephalomyopathies and presents with additional common symptoms, including cerebellar ataxia, cerebrospinal fluid protein levels exceeding 100 mg/dL, deafness, dementia, diabetes, delayed puberty, and amenorrhea

Additionally, research has shown a direct impact of oral functions, such as mastication and swallowing, on life expectancy

Proteomics data associated with this study are publicly available through the MassIVE repository (ID: MSV000095934)

Four studies have reported increased CSF oligomeric -synuclein levels in PD compared with controls (Tokuda et al., 2010