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The good news: visceral fat reduction and IGF-1 effects were similar in people who developed antibodies and those who did not

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[] This PDK-mediated inhibition of pyruvate dehydrogenase shifts mitochondrial metabolism toward reduced glucose oxidation and increased uncoupled glycolysis, promoting RV fibroblasts (RVfib) proliferation, collagen production, and ultimately right ventricular fibrosis and failure