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The parent mutated specific nucleic acid population, either as polynucleotides or cloned into the same vector is introduced into the host cells already containing the daughter nucleic acids

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The dendritic cells and macrophages are responsible for producing cytokines such as TGF-, IL-6, IL-1b, IL-23, and IL-21, which provide an environment for differentiation of Th17 and suppress the differentiation of regulatory T cells (Genovese et al

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