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The focus is increasingly shifting toward: Cellular resilience Tissue regeneration Recovery optimization Inflammation reduction Healthy aging pathways Structural integrity Functional wellness Peptides like GHK-Cu are part of this broader regenerative conversation

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Since SUMO2 is the only essential and most abundantly expressed SUMO paralog in the CNS and sodium arsenite is commonly used to study TDP-43 pathobiology, we focused on TDP-43 SUMOylation by SUMO2 in response to sodium arsenite stress [53, 59]