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10.1016/j.peptides.2015.04.012 8 AzmiA

More specifically, a decrease in various cytokines such as interferon-gamma, IL-6, and IL-12p40 secretion, and an increase in IL-10 secretion was observed, along with low cell-activation status of antigen-presenting cells (APC) and an inhibition of IL-6 and IL-8 production by TLR2 and TLR4-stimulated monocytes in a dose-dependent manner

Copper ionophores, or cuproptosis-related drugs which trigger cuproptosis, may hold promise for future tumor treatments (Table 7) (Springer et al., 2024

Cancer Cell 25 , 719734 (2014)

Any references to skin, collagen, extracellular matrix, or oxidative-stress pathways are provided only for research context and do not imply cosmetic or clinical use