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Chronic Unpredictable Mild Stress for Modeling Depression in Rodents: Meta-Analysis of Model Reliability

To investigate whether ROS are required for chaetocin/TRAIL-induced apoptosis in U87MG and T98G cells, the present study assessed the impact of chaetocin treatment on ROS production

Western diets high in sugar, fat, and n-6 PUFA disrupt the gut barrier by increasing pro-inflammatory mediators, whereas Mediterranean diets rich in dietary fiber, plant polyphenols, and n-3 PUFA enhance microbiota diversity and promote the production of anti-inflammatory metabolites, such as SCFAs, thereby alleviating intestinal inflammation [247,248,249]

Consequently, hydrophobic core-driven aggregation is disrupted, favoring formation of dispersed worm-like micelles stabilized by minimal hydrophobic interactions

Nie A, Chao Y, Zhang X, Jia W, Zhou Z, Zhu C