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Parthanatos has been implicated in a variety of diseases, including CNS disorders, heart disease, diabetes, and inflammatory diseases, where oxidative stress and PARP-1 activation may contribute to cell death, exacerbating pathological processes (Wang et al., 2023a

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3.1.1 CD4+T cells 3.1.1.1Metabolic regulation of Th17/Treg balance Upon antigen activation, nave T cells rapidly initiate metabolic reprogramming, shifting to aerobic glycolysis to support rapid clonal expansion

J Biol Chem (2012) 287(26):2200414

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