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Moreover, Mn-deficient diets exacerbate colitis in mice, whereas Mn supplementation restores epithelial integrity and reduces mucosal injury ( Mn metabolism is also shaped by immune-mediated metal redistribution through nutritional immunity

86 PhpC-containing siRNA shows gene-silencing activity comparable to that of the parent molecule, and its fluorescent properties make it useful for fluorescence-based detection or monitoring or for exploring the cellular uptake and trafficking of siRNA in cells