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Unlike traditional human growth hormone therapy, which can cause increased levels of insulin-like growth factor-1 (IGF-1) and affect blood sugar regulation, AOD-9604 is designed to target fat cells directly

While animal studies show a good safety profile, a theoretical risk involving its pro-angiogenic effects and potential cancer promotion is a point of consideration, though no evidence has supported this risk in practice

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In the future, the identification of specific genes or pathways could serve as direct targets, in conjunction with cysteine deprivation for cancer therapy

doi: 10.3892/br.2016.720 145 HouRC-Wet al