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Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis

Conclusions Mycotoxins simultaneously disrupt gut microbiota composition and liver function, with microbial shiftsparticularly depletion of SCFA-producing and barrier-supportive taxa ( Akkermansia, Roseburia, Prevotella ) and expansion of pro-inflammatory genera (Proteobacteria, Escherichia )compromising intestinal integrity and facilitating endotoxin-driven hepatic oxidative stress and inflammation

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