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During periods of high metabolic demand, intense physical exertion, or cellular stress, the mitochondria can become overwhelmed by partially processed metabolic byproducts, specifically excess acetyl-CoA

Therefore, fish nutritionists have tried different routes to promote the carbohydrate/glucose utilization in fish, including exploring the optimal sources and contents of dietary carbohydrate 41,42 , adding supplementary elements (e.g

(2021) 10:e1183

Indeed exogenous histamine was able to reduce LPS induced inflammation in the hippocampus (Saraiva et al., 2019)

Intravenous administration produced the most pronounced GH, ACTH, and cortisol co-secretion responses