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It can also be used anytime drugs that may be potentially toxic to the pet are administered, especially chemotherapy medicines for treating cancer, heartworm treatment medications, and long-term use of other medications (such as antibiotics and corticosteroids.) The standard dosage of milk thistle is 200 mg, two to three times a day

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The nanocapsules successfully prevented cytotoxicity in keratinocytes, reduced ear thickness in mice, and decreased MPO activity, as well as IL-6 and KC (CXCL 1) concentrations, suggesting the potential of eugenol as a bioactive molecule for improved skin permeation and irritation prevention [79]