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The vagus nerve can also inhibit the release of pro-inflammatory cytokines in such a way that mediates selective cholinergic activation in the inflammatory response, thereby improving inflammation and obesity (97, 98, 105)

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However, most studies have focused solely on its involvement in signaling pathway regulation, neglecting its association with Gln metabolism, and even failing to elucidate its mediating role in Gln-modulated redox homeostasis in tumor cells