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In summary, considering their beneficial effects on gastric emptying, core symptoms and overall symptoms of DGSSD, ghrelin agonists, and relamorelin in particular, show promise as novel and efficient therapies for gastroparesis and other upper GI motility disorders, such as FD and PPI-resistant NERD

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Falutz J, Mamputu JC, Potvin D, et al.: Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: A pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data