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Signs and symptoms, if they do occur, might include fatigue, weakness, pale or yellowish skin, irregular heartbeats, shortness of breath, dizziness or lightheadedness, chest pain, cold hands and feet, and headaches

Cobalamin [Cbl(I)] initially provides two electrons to the catalytic cycle, enabling the energy-dependent transfer of a methyl group from MTHF to Hcy

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Special vitamin B12 requirements during pregnancy, breastfeeding and in old age Pregnant women and breastfeeding mothers also have a higher requirement and must pay particular attention to getting enough vitamin B12, preferably through their normal diet

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