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Mohammad Saeid Hejazi, Ommoleila Molavi, Elahe Pishgahzadeh, and Sevda Jafari cooperated in the final editing and critical review of the manuscript

Anisomycin is a JUN N-terminal kinase (JNK) activator that enhances the phosphorylation of JNK [9, 10] and has significant cytotoxic effects on eukaryotes and some protozoa [6]

E., Lacroix, S., Aviles-Trigueros, M

10.1152/ajprenal.00094.2005 Am

High glutamine impedes growth independent of BRAF status To further test the effect of increased dietary glutamine, we used two melanoma patient-derived xenograft (PDX) models with different genetic backgrounds, PDX_TM00702 (with wild-type BRAF) and PDX_TM01612 (with BRAF V600E mutation), and placed mice on either control or glutamine-rich diet when tumours reached an average of 50 mm 3