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The following results were reported: i) decreased expression of genes related to lymphatic/vascular function, namely Vascular Endothelial Growth Factor C ( Vegfc ) and its cognate receptor Flt4 (Fms Related Receptor Tyrosine Kinase 4) encoding for VEGF receptor 3, and ii) increased expression of genes related to fibrosis and ECM remodeling in thigh SAT compared to abdominal SAT

Date SS, Fiori MC, Altenberg GA, Jansen M

Subsequently, HaCaT keratinocytes viability after treatment with test compounds, GHK, CuCl 2 and Cu(OAc) 2 were assessed using MTT assay and LDH assay

Research Applications (laboratory / non-clinical research only) Animal model research into lipolysis and adipocyte metabolism pathways In vitro studies of fat-cell signaling and triglyceride breakdown mechanisms Preclinical investigation of metabolic rate regulation in rodent models Comparative research into AOD9604 versus full-length growth-hormone research compounds Laboratory studies of cartilage and connective-tissue research models Quality & Sourcing AOD9604 peptide research material is manufactured to high purity standards and verified by HPLC (High-Performance Liquid Chromatography) analysis