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104 Introduction of specific agents under development Among the promising agents under development, Verve Therapeutics is developing in vivo base editing medicines with the goal of inactivating PCSK9 or ANGPTL3

J Cardiovasc Pharmacol (1994) 24(4):64854

While short-term side effects like vertigo, increased body temperature, mood swings, and nausea can occur, long-term side effects are less well-documented due to limited research

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The latter mechanism is triggered by the acidic microenvironment (pH =5.5), which promotes MIL-100 framework degradation, while hyaluronidase (HAase) simultaneously degrades the surface HA layer