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For patients who can't eat enough due to swallowing or breathing problems, a feeding tube (PEG tube) is usually advised while their lung function is still fairly good (when their forced vital capacity is above 50%)

From a biochemical standpoint, pushing the balance too far toward NADH relative to NAD plus can disrupt redox balance, which helps explain why overly aggressive dosing or stacking multiple NAD approaches may increase side effects rather than benefits

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Reducing exposure to high-risk triggers, particularly in early recovery, reduces craving frequency and intensity

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