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TF is aberrantly expressed on a variety of cancer cells and on tumor-associated endothelium, where it contributes to multiple hallmarks of cancer, including sustained proliferation, evasion of cell death, angiogenesis, and activation of invasion and metastasis [89, 97]

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Furthermore, optimal dosing regimens, long-term safety, and pharmacokinetics in humans require further investigation [5]

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Symptoms of low blood sugar, such as sweating, shakiness, confusion, or weakness, should be reviewed promptly