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On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight

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At doses below 5 units (0.05 mL), the percentage error on a syringe becomes significant

Common sites include: Lower abdomen (most common) Upper thigh Upper arm Pinch a fold of skin, insert the needle at a 45-degree angle, and inject slowly over 2-3 seconds