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However, in a human study, TNF- antagonism decreases systemic inflammation but enhances platelet activation, and is not recommended for therapeutic strategy in patients of AMI (128)

Synthesis, molecular modeling investigation, molecular dynamic and ADME prediction of some novel Mannich bases derived from 1,2,4-triazole, and assessment of their anticancer activity

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fluorescence matrix acquired per sample at several excitation/emission wavelengths) were recorded by Synergy 2 Multi-Mode Reader fluorescence spectrometer (BioTek Instruments, Inc., Winooski, VT, USA), using Polystyrene Greiner CELLSTAR 96-well plates (Greiner Bio-One GmbH, Kremsmnster, Austria)