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RGCs, like most neurons, are inherently fragile cells, and a significant source of stress includes suboptimal nutrient support, oxidative stress, and pH changes in their culture media during short-term storage while waiting for the transplantation procedure

It can be classified as acute when referring to a beneficial process that helps to immobilize a lesioned region and allows the rest of the immune system to be activated to heal lesions, or it can be classified as chronic, which can become a problem and not a solution for lesions since chronically inflamed tissues normally induce immune cells in the bloodstream to amplify the inflammatory response, which can destroy healthy tissues in an erroneous attempt to start the repair process (Figure 2) [55]

PMID: 70 LuQLouJCaiRHanWPanH

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[3] While both medications show promise, tirzepatides more extensive phase III data currently provides a deeper evidence base compared to mazdutides ongoing trials