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And we keep having to use our clinical judgment, rather than trusting blindly on test results 5

Using both is redundant rather than synergistic and may cause NAD+ oversupply, which preliminary research suggests could impair SIRT1 regulation

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Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome

If you suspect an adverse reaction to Mounjaro or any other medication, you can report this through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)