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The substrates of this alteration are directed to the polyol pathway, which, at normal glucose concentrations, is not active [38]

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Therefore, it has been suggestion that increased selenium consumption may be associated with an increased risk of developing diabetes (115)

As per the latest diagnostic criteria, MetS necessitates the presence of any three out of the following five conditions: elevated fasting glucose or type 2 diabetes (T2D), hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol levels, central obesity, or hypertension (Alberti et al., 2009)