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A similar trend was observed with methoxy substitution ( 59 61 ) and dimethylaniline ( 62 64 ) with 4-position not being tolerated

Collectively, TSZW alleviates hepatic and neurological aging via Nrf2/ARE-mediated antioxidant signaling, with concurrent mitigation of systemic aging phenotypes, including immune organ atrophy and chronic inflammation

Salari N, Rasoulpoor S, Rasoulpoor S, Shohaimi S, Jafarpour S, Abdoli N, et al

Notably, LBP has been shown to mitigate the pathological changes of mitochondria, protect RCG morphology and ultrastructure, inhibit neuronal apoptosis, and prevent the transition from nerve to vascular injury via its antioxidant properties, suggesting a potential therapeutic role in early-stage DR intervention (96) (Figure 6)

doi: 10.1016/j.bcp.2013.12.024