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Discussion This study showed that a short course of sublingual vitamin B12, 1000 mcg daily, can significantly improve the severity of FM as well as the anxiety score of FM patients

Disclosure of interest: None Poster Session II - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.02 - ACUTE MANAGEMENT - Thrombolysis or thrombectomy P682 - ESOC25-1141 RISK OF SYMPTOMATIC INTRACRANIAL HEMORRHAGE IN ENDOVASCULAR STROKE TREATMENT: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS Joo Andr Sousa 1 , Sara Bernardo-Castro 2 , Joao Nuno Ramos 3 , Helena Donato 4 , Joo Sargento Freitas 1 1 Stroke Unit, Unidade Local de Sade de Coimbra, Portugal, Coimbra, Portugal, 2 IISPV Pere Virgili Health Research Institute, Tarragona, Spain, 3 Diagnostic Neuroradiology Unit, Imaging Department, Unidade Local de Sade Gaia e Espinho, Vila Nova de Gaia, Portugal, Vila Nova de Gaia, Portugal, 4 Documentation and Scientific Information Service, Hospitais da Universidade de Coimbra, Unidade Local de Sade de Coimbra, Portugal, Coimbra, Portugal Background and Aims: Symptomatic intracranial hemorrhage (sICH) is a key safety outcome in endovascular therapy (EVT) for acute ischemic stroke (AIS)

More than 1,400 adults are expected to be enrolled in the trial, likely to be in the United States

These include Dr