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This neuroimmune-tumor connection is also paradoxical as links also exists between chronic inflammation and tumorigenesis, with glioma cells producing pro-inflammatory cytokines, chemokines, and growth factors that create an inflammation-enriched TME (65, 66)

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doi: 10.3390/ijms23031105

In HIV infected macrophages, while fatty acids and glucose were still utilized, the contribution of glutamine sources significantly increased (Fig