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Third, innovative clinical trials should be meticulously designed, such as "basket trials" or "platform trials" that use biomarker enrichment strategies to rapidly validate the efficacy of targeted strategies in small patient populations

In addition, drug development targeting the gut-brain axis is in the exploratory phase

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Although CS-PDMS films have been developed as laser ultrasound transducers 2325 , our study represents the first instance of engineering them into a sandwich-structure

The example math below uses 3.0 mL of bacteriostatic water per 50 mg vial, which gives roughly 16.7 mg/mL of compound in solution