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Atrial RONS sources include the NADPH oxidase, xanthine oxidase, uncoupled nitric oxide synthase, myeloperoxidase (MPO), and the mitochondrial electron transport chain

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For instance, beyond their DHAR activity, fungal and bacterial GHRs characterized so far efficiently reduce glutathionylated (chlorinated) (hydro)quinones with k cat around 10 3 s 1 and k cat / K m up to 10 6 M 1 .s 1 (Table 5) (Huang et al., 2008

As PD progresses, poor resolution, continuous peripheral immune noise, and -syn-driven cellular stress combine to alter the CNS milieu from adaptive neuroprotection to chronic neuroinflammation