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We would not expect a close match to the clinically observed percentage changes because we are comparing intracellular model changes to blood measurements

Other organ system-based : Causes can come from the kidneys (e.g., stones), reproductive system (e.g., ovaries), or gastrointestinal system (e.g., inguinal hernias, appendix)

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Johnson, Rhode Island

Pharmacovigilance analysis identified that patient age and body weight were significantly associated with gastrointestinal adverse event severity, with patients over 100 kg showing stronger signal strength for adverse events