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Group 1 was a vehicle control that received an intravenous injection of saline

Comp Biochem Physiol C Toxicol Pharmacol 155:469482 Crouch RK, Gandy SE, Kimsey G et al (1981) The inhibition of islet superoxide dismutase by diabetogenic drugs

Vincristine induces the expression of integrins (immune markers) on the surface of endothelial cells which allows macrophages expressing the CX3CR receptor to adhere to the endothelium and to migrate into nervous tissue