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The study contributed to a developing preclinical literature suggesting AOD-9604 may have applications in joint and cartilage research distinct from its original metabolic indication

doi: 10.1093/nar/gky427 [DOI] [PMC free article] [PubMed] [Google Scholar] 36.Giulianelli S, Molinolo A, Lanari C

People who are unable to absorb vitamin B-12 properly may have pernicious anemia, which is a type of anemia characterized by a lack of intrinsic factor

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COMT inhibitors (COMT-I) can rebalance this abnormal metabolic loop by suppressing the overproduction of SAH by COMT after LDopa administration and lowering Hcy levels (Cossu et al