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1f, and Supplementary Fig

5fi and Extended Data Fig

Form of B12: Many clinics use cyanocobalamin (a synthetic form of B12 which requires a number of conversions) for their B12 shots

Hence, SIDT2 is regarded to be the more important of the two 116

Specifically, large molecules and more than 98% of low-molecular-weight drugs face difficulties permeating the BBB, resulting in low brain bioavailability