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Oe S, Miyagawa K, Honma Y, Harada M (2016) Copper induces hepatocyte injury due to the endoplasmic reticulum stress in cultured cells and patients with Wilson disease

Reconstitution Steps (Both Vials) Remove the vial from freezer storage (20 C / 4 F) and allow to equilibrate at room temperature for 1520 minutes

About one in 20 men have low numbers of sperm which is one of the common causes for infertility

Advise males with female partners of reproductive potential to use effective contraception during treatment with pemetrexed and for 3 months after the last dose [see Use in Specific Populations (8.1, 8.3) and Clinical Pharmacology (12.1)]