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The phenomenon of mitochondrial transfer between neurons and astrocytes, as observed by Ni et al., is seen as one of the potential hopes that we can take advantage of for neuronal survival during ischemic brain injury [122]

We obtained GWAS data on mtDNA-CN (Supplementary Table S1, GWAS ID: ebi-a-GCST90026372, sample size: 383,476) and mitochondrial-related protein datasets (Sun et al., 2018) (a total of 64 proteins and 66 datasets are included, of which MUL1 and AIFM1 each contain two GWAS datasets) from the openGWAS database ( accessed on 10 May 2024)

The working theory is that when adipocytes get their SAM and NAD+ back, they stop hoarding fat and start behaving like normal, energy-burning cells again

B., Meister, J