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In fact, MTHFR variants are tentatively linked to being more likely to have problems detoxifying mercury (small study).[ref][ref] Related article: Mercury detoxification genes Tradeoffs

2 Although product information approved by the US Food and Drug Administration for nonantimicrobial sulfonamides may include warnings about possible cross-reaction with antimicrobial sulfonamides, 1 these drugs do not need to be withheld